Recent research studies indicate that Vitamin D deficiency can lead to a loss of bone density, which can contribute to osteoporosis and fractures . It can also cause osteomalacia, which is lean bones. Lean bones are weak bones that cause pain and muscle weakness.
Severe vitamin D deficiency can also lead to other diseases. In children, it can cause rickets. Rickets is a rare disease that causes the bones to become soft and bend. In women, it can cause hair loss and headaches.
Researchers are studying vitamin D for its possible connections to several medical conditions, including diabetes, drug-resistant high blood pressure, cancer, resisting obesity, depression, insomnia and autoimmune conditions.
In case of vitamin D deficiency, 57357 Patients and non- patients can consult on the treatment plan at the Nutritional therapy department’s Vitamin D clinic located on the first floor twice a week on Sundays and Wednesdays from 4pm to 6pm. Cost of the visit is L.E.120.
The Proteomics Unit at Hospital 57357, the first proteomics laboratory in Egypt and the Middle East, is equipped with top-notch facilities and empowered with a fine selection of specialized scientists with solid experience.
The unit aims at empowering research by precise qualitative and quantitative protein identification using high-end state- of- art Proteomics technology. The unit offers several specialized and comprehensive services, solutions and packages. Their uniqueness stems from the fact that they are simply the only ones offering these services in Egypt. Costs include reagents, sample processing, manpower, instrument usage, data analysis and reporting.
The proteomics unit believes that innovation is a group endeavor. That is why it is collaborating with the top scientists in Egypt and worldwide. Their collaboration is expanding and they are always welcoming a powerful collaboration targeting high impacted scientific journals. Present collaborations include: Zewail city of science and technology, Zewail city of science and technology, Armed forces college of Medicine, Urology and nephrology center, Mansoura, Baylor College of Medicine, USA University of Rochester, USA, Niigata University, Japan, Fred Hutchinson cancer research center, Seattle and Baylor University, USA.
Services and Costs
We offer a unique service with different assay length and applications. Our uniqueness stems from the fact that we are simply the only ones offering these services in Egypt. Costs include reagents, sample processing, manpower, instrument usage, data analysis and reporting.
We work professionally according to world standards to ensure accurate, sensitive results. For all samples, we perform an efficient protein extraction using varieties of extraction buffers, quantification of proteins and appropriate protein reduction and alkylation prior to trypsinization. All samples are subjected to C18 desalting step to make sure purified peptides are going to our clean TripleTOF 5600+.
Data is searched by up to two tandem mass spectrometry protein identification algorithms, including X!Tandem, OMSSA, comet, tide, andromeda.
Label free quantification based on spectral abundance “NSAF or emPAI” or area under the curve “AUC” is provided free of charge.
Samples or groups of samples are compared, generating fold-change values for every measured protein.
NGS is an advanced technology that refers to high throughput genome assays at high accuracy and reasonable price. It does not only produce massive amount of genetic information, but it also establishes a foundation for personalized genomic medicine as a part of standard medical care.
It is a tool that helps in providing precise medical diagnosis of genetic diseases and in transforming genetic information into actionable results for physicians and patients.
MiSeq DX is an FDA regulated and CE-IVD marked sequencer for invitro diagnostic testing.
It can be used for Targeted Gene Panel: A select set of genes or gene regions that have proven or suspected associations with the disease or phenotype under study.
HiSeq: has both rapid run mode and high output run mode can generate from 10 gigabase to 1 terabase per run capacity
Whole genome sequencing.
Provides a high-resolution, base-by-base view of the genome which is highly informative in cancer and hereditary conditions.
NGS Gene panels:
Genetic testing for hereditary cancer.
Familial breast cancer, Hereditary breast and ovarian cancer, Familial male breast cancer.
Hereditary thyroid cancer.
Hereditary non-polyposis colorectal cancer.
Hereditary brain tumors.
Mismatch repair cancer syndrome.
Neurofibromatosis Type 1 & 2.
Bone marrow Failure:
Caused by many genetic mutations resulting in reduced or abnormal production of one or more of the three blood cell types (red blood cell, white blood cell and platelets).
Example: Fanconi anemia, Dyskeratosis congenita, Diamond Blackfan anemia and Shwachman Diamond syndrome. There may be increased risk of cancer development.