Continued">Continued">Continued">Latest News / Updates – Children Cancer Hospital Egypt 57357

Latest News / Updates

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents August 26, 2020

Abstract BACKGROUND Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus disease 2019 (Covid-19) is important, given the clinical and public health implications of the syndrome. METHODS We conducted targeted surveillance for MIS-C from March 15 to May 20, 2020, in pediatric health centers across … Continued

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19 August 23, 2020

Key Points Question  Does remdesivir provide a benefit on clinical status for patients hospitalized with moderate coronavirus disease 2019 (COVID-19) pneumonia? Findings  In this randomized, open-label, phase 3 trial that included 584 patients with moderate COVID-19, the day 11 clinical status distribution measured on a 7-point ordinal scale was significantly better for those randomized to a 5-day … Continued

COVID-19 in solid organ transplant: A multi-center cohort study August 14, 2020

Abstract Background: The COVID-19 pandemic has led to significant reductions in transplantation, motivated in part by concerns of disproportionately more severe disease among solid organ transplant (SOT) recipients. However, clinical features, outcomes, and predictors of mortality in SOT recipients are not well-described. Methods: We performed a multi-center cohort study of SOT recipients with laboratory-confirmed COVID-19. Data were … Continued

Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes

Key Points Question  What are the safety and immunogenicity of an inactivated vaccine against coronavirus disease 2019 (COVID-19)? Findings  This was an interim analysis of 2 randomized placebo-controlled trials. In 96 healthy adults in a phase 1 trial of patients randomized to aluminum hydroxide (alum) only and low, medium, and high vaccine doses on days 0, 28, … Continued

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections July 28, 2020

Abstract The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic individuals in the Wanzhou District who were diagnosed with RT–PCR-confirmed SARS-CoV-2 infections but without any relevant clinical symptoms in the preceding 14 d and during hospitalization. Asymptomatic … Continued

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19 July 24, 2020

TO THE EDITOR: A recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection,1 but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves to our institution for observational research. Written informed consent was obtained from all the participants, with approval by the institutional review … Continued

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

BACKGROUND The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine. The candidate vaccine mRNA-1273 encodes the stabilized prefusion SARS-CoV-2 spike protein. METHODS We conducted a phase 1, dose-escalation, open-label trial including 45 healthy adults, 18 to 55 years of … Continued

التعامل مع الشدائد و الازمات July 22, 2020

رسايل ربنا حوالينا كتير لا تعد ولا تحصى الشيخ محمود الشبكي هيكلمنا عن الازمات و ازاي افضل خلق الله رسولنا الكريم قدر يقرأ رسايل ربنا ليه وحول الشدائد والازمات لنجاح 

A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 July 15, 2020

Abstract In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID‐19). This disease, caused by the severe acute respiratory syndrome–related coronavirus 2 (SARS‐CoV‐2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID‐19 pandemic is the gravest … Continued

OpenSAFELY: factors associated with COVID-19 death in 17 million patients July 14, 2020

Article – Published: 08 July 2020 This is an unedited manuscript that has been accepted for publication. Nature Research are providing this early version of the manuscript as a service to our authors and readers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that … Continued